A 57-year-old female with a history of IV drug use, chronic hepatitis B and C with cirrhosis, coronary artery disease, hypothyroidism, obesity, chronic Pyoderma Gangrenosum (PG), lipodermatosclerosis, and elephantiasis nostras verrucosa who presented to the ED with a flare of her PG. She had chronic bilateral lower extremity ulcers for 2 years that had not fully healed (Figure 1A & 1D).
Tracheoesophageal Fistulas (TEF) are congenital abnormalities of the foregut characterized by an aberrant communication between the esophagus and trachea with subtypes further classified by the presence of esophageal atresia [1]. Symptoms consistent with TEFs typically appear soon after birth and may include respiratory distress, cyanosis, coughing, choking during ..
Prurigo Nodularis (PN) is a chronic pruritic skin disorder characterized by intensely itchy, hyperpigmented nodules that develop often as a consequence of repeated scratching [1,2]. The pathogenesis of PN involves complex neuroimmune dysregulation, including elevated levels of Interleukin-31 (IL-31), a key mediator of pruritus, and interactions between the peripheral nervous system ..
Methemoglobinemia is a disorder characterized by the oxidation of iron within hemoglobin from the Ferrous (Fe2+) to the Ferric (Fe3+) state, impairing its ability to bind and transport oxygen and resulting in functional hypoxia despite adequate circulating oxygen levels [1,2]. Clinically, patients often present with cyanosis that is refractory to supplemental ..
Neonatal sepsis is a significant cause of neonatal morbidity and mortality worldwide, and its symptoms are often nonspecific. Therefore, inflammatory markers such as CRP, IL-6, PCT, WBC and others, measured in peripheral blood, are used for its diagnosis. Recent analyses emphasize the role of interleukin-6 in the immune response and acute-phase reactions.
A 78-year-old man presented with transient epigastric pain that had started 10 days earlier. His medical history included emphysema, hypertension, and dyslipidemia. On admission, vital signs were normal except for severe bradycardia (heart rate, 35 beats/min). Electrocardiography showed complete atrioventricular block with ST-segment elevation ..
Peer review is an essential process in any publications refereeing a mutual process that allows evaluating manuscripts submitted to a journal and commented upon by independent research experts within the similar field of research...
Open Access is the free of charge, instant, online availability of research articles, together with the rights to use these articles fully in the digital milieu. It provides unrestricted use and reuse...
Plagiarism is a part of Journalistic ethic where it is considered to be a crime. The act of taking content, writing, statement or an idea that is already published is known as plagiarism. Whenever you consider using any paraphrase, sum up, or take terms, phrases, sentences or statements...